Adaptation of the cardiovascular system of infants born by mothers with diabetes mellitus

It is known, that diabetes mellitus has a significant impact on the growth and development of fetus. Hyperglycemia during pregnancy increases significantly incidence congenital malformations, perinatal morbidity neonatal mortality. Over past decades been steady increase in prevalence both general population among pregnant women. In this regard, study influence mother condition fetus newborn today relevant problem obstetric-gynecological, neonatological pediatric services. greatest effect fetal cardiovascular system. Diabetes causes an frequency heart defects newborn, myocardial hypertrophy, as well various functional disorders This review mainly discusses pathogenetic aspects molecular mechanisms hyperglycemia heart, provides assessment clinical, echocardiographic some laboratory changes functioning system newborns from mothers with mellitus, also systematizes data relationship between maternal risks disease their children long term.